AboutInVivoMAbanti-mouseE-selectin(CD62E)
The9A9monoclonalantibodyreactswithmouseE-selectinalsoknownasCD62E,endothelial-leukocyteadhesionmolecule1(ELAM-1),andleukocyte-endothelialcelladhesionmolecule2(LECAM2).E-selectinisa115kDatypeItransmembraneproteinandamemberoftheselectinfamilyofadhesionmolecules.E-selectinisexpressedoncytokine-activatedendothelialcells.AlongwithL-selectinandP-selectin,E-selectinmediatestheinitialinteractionsofleukocytesandplateletswithendothelialcells.E-selectinisthoughttoplayaroleininflammation,tumormetastasis,andangiogenesis.The9A9antibodyhasbeenshowntoreducethemigrationefficiencyofTh1cellsandblockE-selectin-mediatedrolling.
InVivoMAbanti-mouseE-selectin(CD62E)Specifications
| Isotype | RatIgG2B |
| RecommendedIsotypeControl(s) | InVivoMAbratIgG2bisotypecontrol,anti-keyholelimpethemocyanin(BE0090) |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer(IP0070) |
| Immunogen | COS-expressed,recombinantmouseE-selectin |
| ReportedApplications |
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| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2μmfiltration |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinG |
| Storage | Theantibodysolutionshouldbestoredundilutedat4°C,andprotectedfromprolongedexposuretolight.Donotfreeze. |
| RRID | AB_2687816 |
