AboutInVivoMAbanti-mouseCD106(VCAM-1)
TheM/K-2.7monoclonalantibodyreactswithCD106alsoknownasVCAM-1andINCAM-110.CD106isa110kDasinglechaintypeIglycoproteinthatisexpressedprimarilyonactivatedvascularendothelialcellsbuthasalsobeenreportedonfollicularandinterfolliculardendriticcells,somemacrophages,bonemarrowstromalcells,andnon-vascularcellpopulationswithinjoints,kidney,muscle,heart,placenta,andbrain.CD106expressionisinducedbyinflammatorystimuliandcytokines.CD106bindstheintegrinsCD49d/CD29(VLA-4)andα4β7whichcontributetoleukocyteadhesion,transmigration,andco-stimulationofTcellproliferation.
InVivoMAbanti-mouseCD106(VCAM-1)Specifications
| Isotype | RatIgG1, κ |
| RecommendedIsotypeControl(s) | InVivoMAbratIgG1isotypecontrol,anti-horserADIshperoxidase(BE0088) |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer(IP0070) |
| Immunogen | Stromalcellsfrommousebonemarrow |
| ReportedApplications |
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| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2μMfiltered |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinG |
| Storage | Theantibodysolutionshouldbestoredundilutedat4°C,andprotectedfromprolongedexposuretolight.Donotfreeze. |
| RRID | AB_1107572 |
