AboutInVivoMAbanti-humanE-Selectin
TheCL2monoclonalantibodyreactswithhumanE-selectinalsoknownasCD62E,endothelial-leukocyteadhesionmolecule1(ELAM-1),andleukocyte-endothelialcelladhesionmolecule2(LECAM2).E-selectinisa115kDatypeItransmembraneproteinandamemberoftheselectinfamilyofadhesionmolecules.E-selectinisexpressedoncytokine-activatedendothelialcells.AlongwithL-selectinandP-selectin,E-selectinmediatestheinitialinteractionsofleukocytesandplateletswithendothelialcells.E-selectinisthoughttoplayaroleininflammation,tumormetastasis,andangiogenesis.TheCL2antibodyhasbeenshowntoinhibitneutrophiladhesiontoE-selectinandtoP-selectin.
InVivoMAbanti-humanE-SelectinSpecifications
| Isotype | MouseIgG2a, κ |
| RecommendedIsotypeControl(s) | InVivoMAbmouseIgG2aisotypecontrol,unknownspecificity(BE0085) |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer(IP0070) |
| Immunogen | Notavailableorunknown |
| ReportedApplications | Flowcytometry |
| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2μMfiltered |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinG |
| Storage | Theantibodysolutionshouldbestoredundilutedat4°C,andprotectedfromprolongedexposuretolight.Donotfreeze. |
| RRID | AB_10949619 |
