AboutInVivoMAbanti-mouseCD276(B7-H3)
TheMJ18monoclonalantibodyreactswithmouseCD276alsoknownasB7-H3.CD276isatypeItransmembraneproteinandamemberoftheB7familyofco-stimulatoryproteins.CD276isexpressedweaklyonactivatedlymphocytes,macrophages,dendriticcells,nasalandairwayepithelialcells,osteoblasts,andsometumorcelllines.AsolubleformofCD276isalsosecretedbymonocytes,dendriticcells,andactivatedTcells.TheBIOLOGicalroleofCD276isstillunderinvestigationhowever,recentstudiessuggestanegativeregulatoryroleforCD276inTcellresponses.TheMJ18antibodyhasbeenshowntoblockCD276whenadmiNISTeredinvivo.
InVivoMAbanti-mouseCD276(B7-H3)Specifications
| Isotype | RatIgG1, κ |
| RecommendedIsotypeControl(s) | InVivoMAbratIgG1isotypecontrol,anti-horserADIshperoxidase(BE0088) |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer(IP0070) |
| Immunogen | MouseB7-H3IgG2afusionprotein |
| ReportedApplications |
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| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2μMfiltered |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinG |
| Storage | Theantibodysolutionshouldbestoredundilutedat4°C,andprotectedfromprolongedexposuretolight.Donotfreeze. |
| RRID | AB_10950149 |
