AboutInVivoMAbanti-mouseCD4
TheYTS191monoclonalantibodyreactswithmouseCD4.TheCD4antigenisa55kDatypeIcell-surfacemembraneglycoproteinbelongingtotheimmunoglobulinsuperfamily.CD4actsasaco-receptorwhichincooperationwiththeTcellreceptor(TCR)interactswithclassIIMHCmoleculesdisplayedbyantigenpresentingcells(APC).CD4isexpressedbythemajorityofthymocytes,mosthelperTcells,asubsetofNK-Tcellsandweaklybydendriticcellsandmacrophages.CD4playsanimportantroleinthedevelopmentofTcellsandisrequiredformatureTcellstofunctionoptimally.TheYTS191antibodyhasbeenshowntocompetewithclonesGK1.5andYTS177forCD4binding.
InVivoMAbanti-mouseCD4Specifications
| Isotype | RatIgG2b, κ |
| RecommendedIsotypeControl(s) | InVivoMAbratIgG2bisotypecontrol,anti-keyholelimpethemocyanin(BE0090) |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer(IP0070) |
| Immunogen | Notavailableorunknown |
| ReportedApplications | invivoCD4+Tcelldepletion |
| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2μMfiltered |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinG |
| Storage | Theantibodysolutionshouldbestoredundilutedat4°C,andprotectedfromprolongedexposuretolight.Donotfreeze. |
| RRID | AB_10950382 |
