AboutInVivoMAbanti-mouseIL-17F
TheMM17F8F5.1A9(alsoknownasMM17F-8F5)monoclonalantibodyreactswithmouseIL-17Fa37kDacytokineexpressedbyTh17cells,γδTcells,mastcells,basophils,andepithelialcells.IL-17FcanbesecretedashomodimersorasheterodimerswithIL-17A.IL-17FandIL-17Ahaveoverlappingfunctions.Bothplayanimportantroleinanti-microbialandchronicinflammationbyinducingcytokineandchemokineproduction,neutrophilinflux,andtheproductionofantibacterialpeptides.OverexpressionofIL-17Fisassociatedwithairwayhyperreactivityandmucushypersecretion.TheMM17F8F5.1A9antibodyhasbeenshowntoneutralizeIL-17Finvivo.
InVivoMAbanti-mouseIL-17FSpecifications
| Isotype | MouseIgG1,κ |
| RecommendedIsotypeControl(s) | InVivoMAbmouseIgG1isotypecontrol,unknownspecificity(BE0083) |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer(IP0070) |
| Immunogen | MouseIL-17F |
| ReportedApplications |
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| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2μmfiltration |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinA |
| Storage | Theantibodysolutionshouldbestoredundilutedat4°C,andprotectedfromprolongedexposuretolight.Donotfreeze. |
| RRID | AB_2715461 |
