AboutInVivoMAbanti-mouseCD45.2
The104.2monoclonalantibodyreactswithmouseCD45.2a180-240kDamemberoftheproteintyrosinephosphatasefamily.CD45.2isanalloantigenofCD45andisonlyexpressedbycertainmousestrainsincludingC57BL/6,CBA,129,A,AKR,C58,DBA/1,DBA/2,BALB/c,andC3H/He.The104.2monoclonalantibodydoesnotreactwithleukocytesofCD45.1-expressingmousestrainsincludingDA,SJL/J,RIII,andSTS/A.CD45.2isexpressedonallhematopoieticcellsexceptmatureerythrocytesandplateletsandisthoughttobeinvolvedinTCRandBCRsignaltransduction.The104.2antibodyhasbeenshowntoblockBcellresponsesinvitroandreduceserumautoantibodyconcentrationinvivoinSLE-pronemice.
InVivoMAbanti-mouseCD45.2Specifications
| Isotype | MouseIgG2a,κ |
| RecommendedIsotypeControl(s) | InVivoMAbmouseIgG2aisotypecontrol,unknownspecificity(BE0085) |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer(IP0070) |
| Immunogen | B10.Smousethymocytesandsplenocytes |
| ReportedApplications |
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| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2μmfiltration |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinG |
| Storage | Theantibodysolutionshouldbestoredundilutedat4°C,andprotectedfromprolongedexposuretolight.Donotfreeze. |
| RRID | AB_2715458 |
