AboutInVivoMAbanti-mouseCD1d(CD1.1)
The19G11monoclonalantibodyreactswithmouseCD1dalsoknownasCD1.1.CD1disa48kDatypeImembraneglycoproteinandamemberoftheCD1familyofglycoproteins.CD1disanon-classicalMHCproteinwithstructuralhomologytoclassIMHCmolecules.CD1disexpressedonthesurfaceofvariousantigen-presentingcellsandisinvolvedinthepresentationofnon-peptideglycolipidantigenstotoCD1d-restrictedTcells.CD1d-presentedglycolipidantigensactivateinvariantnaturalkillerT(iNKT)cells,throughtheinteractionwiththeT-cellreceptorpresentoniNKTcellmembranes.Whenactivated,iNKTcellsrapidlyproduceTh1andTh2cytokines.
InVivoMAbanti-mouseCD1d(CD1.1)Specifications
| Isotype | RatIgG2b, κ |
| RecommendedIsotypeControl(s) | InVivoMAbratIgG2bisotypecontrol,anti-keyholelimpethemocyanin(BE0090) |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer(IP0070) |
| Immunogen | MouseCD1d |
| ReportedApplications | invivoCD1dneutralization |
| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2μMfiltered |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinG |
| Storage | Theantibodysolutionshouldbestoredundilutedat4°C,andprotectedfromprolongedexposuretolight.Donotfreeze. |
| RRID | AB_1107568 |
