AboutInVivoMAbanti-mouse/humanVLA-4(CD49d)
ThePS/2monoclonalantibodyreactswithhumanandmouseVLA-4αchainalsoknownasCD49dandintegrinalpha4.VLA-4isa150kDaglycoproteinbelongingtotheintegrinfamilythatisexpressedbymanycelltypesincludingTandBlymphocytes,monocytes,eosinophils,basophils,mastcells,thymocytes,NKcells,anddendriticcells.Integrinα4associateswithintegrinβ7toformintegrinα4β7alsoknownasLPAM-1aswellasintegrinβ1(CD29)toformintegrinα4β1alsoknownasVLA-4.Integrinα4playsrolesinadhesionandTcellco-stimulation.Integrinα4ligandsincludeVCAM-1,MAdCAM-1,andfibronectin.ThePS/2antibodyisusefulforinvivoandinvitroVLA-4neutralization.
InVivoMAbanti-mouse/humanVLA-4(CD49d)Specifications
| Isotype | RatIgG2b, κ |
| RecommendedIsotypeControl(s) | InVivoMAbratIgG2bisotypecontrol,anti-keyholelimpethemocyanin(BE0090) |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH6.5DilutionBuffer(IP0065) |
| Immunogen | MouseP815mastcells |
| ReportedApplications |
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| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2μMfiltered |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinG |
| Storage | Theantibodysolutionshouldbestoredundilutedat4°C,andprotectedfromprolongedexposuretolight.Donotfreeze. |
| RRID | AB_1107657 |
