AboutInVivoMAbanti-mouseTCRγ/δ
TheUC7-13D5monoclonalantibodyreactswithanepitopeonthemouseγ/δTCR(gammadeltaTcellreceptor)complex.Theγ/δTCRisexpressedbyasubsetofTcellsfoundinthethymus,peripherallymphoidtissues,intestinalepithelium,epidermis,andperitoneum.Theexactfunction,ligand,andspecificityofγ/δTCR-expressingTcellsarenotcompletelyunderstood.StudiessuggestthatthesecellsrecognizebacterialligandsandsometumorcellsinthecontextofMHCclassI-likegeneproductsandplayaroleinregulatingtheimmuneresponseduringbacterialinfection.TheUC7-13D5antibodyhasbeenshowntoactivateγ/δTcellsinvitroanddepleteγ/δTcellswhenadmiNISTeredinvivo.
InVivoMAbanti-mouseTCRγ/δSpecifications
| Isotype | ArmenianHamsterIgG, κ |
| RecommendedIsotypeControl(s) | InVivoMAbpolyclonalArmenianhamsterIgG(BE0091) |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH6.5TDilutionBuffer(IPT065) |
| Immunogen | Notavailableorunknown |
| ReportedApplications |
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| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2μMfiltered |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinA |
| Storage | Theantibodysolutionshouldbestoredundilutedat4°C,andprotectedfromprolongedexposuretolight.Donotfreeze. |
| RRID | AB_1107751 |
