AboutInVivoPlusanti-mouseCD4
TheGK1.5monoclonalantibodyreactswiththemouseCD4.TheCD4antigenisa55kDacellsurfacetypeImembraneglycoproteinbelongingtotheimmunoglobulinsuperfamily.CD4actsasaco-receptorwhichincooperationwiththeTcellreceptor(TCR)interactswithclassIIMHCmoleculesdisplayedbyantigenpresentingcells(APC).CD4isexpressedbythemajorityofthymocytes,mosthelperTcells,asubsetofNK-Tcellsandweaklybydendriticcellsandmacrophages.CD4playsanimportantroleinthedevelopmentofTcellsandisrequiredformatureTcellstofunctionoptimally.TheGK1.5antibodyhasbeenshowntocompetewithclonesYTS177andYTS191forCD4binding.
InVivoPlusanti-mouseCD4Specifications
| Isotype | RatIgG2b, κ |
| RecommendedIsotypeControl(s) | InVivoPlusratIgG2bisotypecontrol,anti-keyholelimpethemocyanin(BP0090) |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH6.5DilutionBuffer(IP0065) |
| Immunogen | MouseCTLcloneV4 |
| ReportedApplications |
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| Endotoxin |
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| BindingValidation | Determinedbyimmunoblot |
| Purity |
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| Aggregation |
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| Formulation |
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| Sterility | 0.2μMfiltered |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinG |
| Storage | Theantibodysolutionshouldbestoredundilutedat4°C,andprotectedfromprolongedexposuretolight.Donotfreeze. |
| MurinePathogenTestResults |
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| RRID | AB_1107636 |
