About InVivoMAb anti-mouse/human IL-5
The TRFK5 monoclonal antibody reacts with mouse and human interleukin-5 (IL-5), a 26 kDa homodimeric cytokine. IL-5 stimulates B lymphocyte differentiation and proliferation and increases the secretion of IgM and IgA. It is also a key mediator in eosinophil activation and differentiation. IL-5 has long been associated with the cause of several allergic diseases including allergic rhinitis and asthma, wherein a large increase in the number of circulating, airway tissue, and induced sputum eosinophils have been observed. The TRFK5 antibody has been shown to neutralize the bioactivity of natural or recombinant IL-5.
InVivoMAb anti-mouse/human IL-5 Specifications
| Isotype | Rat IgG1, κ |
| Recommended Isotype Control(s) | InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase(BE0088) |
| Recommended InVivoPure Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer(IP0070) |
| Immunogen | Mouse partially-purified T cell clone supernatant |
| Reported Applications |
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| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2 μM filtered |
| Production | Purified from tissue culture supernatant in an animal free facility |
| Purification | Protein G |
| Storage | The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze. |
| RRID | AB_10950522 |
