The J11d monoclonal antibody reacts with mouse CD24 also known as heat stable antigen (HSA), a 35-50 kDa glycosylated membrane protein. CD24 is expressed by erythrocytes, granulocytes, monocytes, and lymphocytes. Immature B cells in bone marrow and spleen of adult mice express high levels of CD24, while mature peripheral B cells express intermediate levels of CD24. The expression of CD24 has been used to resolve stages of B cell lymphopoiesis in mouse bone marrow. It has been reported that P-selectin (CD62P) binds to CD24. The J11d antibody has been shown to deplete CD24+ cells when administered in vivo.
| Isotype | Rat IgM, κ |
| Recomended Isotype Control(s) | InVivoMAb polyclonal rat IgG |
| Recommended InVivoPure Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
| Immunogen | C3H/HeJ mouse thymocytes |
| Reported Applications | in vitro CD24+ cell depletion |
| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2 μM filtered |
| Production | Purified from tissue culture supernatant in an animal free facility |
| Purification | T-Gel |
| Storage | Undiluted at 4°C in the dark |
