
BioX细胞/InVivoMAb抗小鼠4-1BB(CD137)/BE0239/100MG
商品编号:
BE0239
品牌:
BioXcell inc
市场价:
¥61600.00
美元价:
36960.00
产品分类:
单克隆抗体
公司分类:
monoclonal_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
The3H3monoclonalantibodyreactswithmouse4-1BB,aTNFreceptorsuperfamilymemberalsoknownasCD137.4-1BBisa39kDatransmembraneproteinexpressedbyTlymphocytes,NKcells,dendriticcells,granulocytes,andmastcells.Uponbindingitsligand4-1BBL,4-1BBprovidescostimulatorysignalstobothCD4andCD8TcellsthroughtheactivationofNF-κB,c-Junandp38downstreampathways.Theimportanceofthe4-1BBpathwayhasbeenunderscoredinanumberofdiseases,includingcancer.AgoNISTicanti-4-1BBantibodieshavebeenreportedtoinduceTcellmediatedantitumorimmunity.The3H3antibodyisanagonisticantibodythathasbeenshowntostimulate4-1BBsignalinginvivo.
Isotype | RatIgG2a |
RecomendedIsotypeControl(s) | InVivoMAbratIgG2aisotypecontrol,anti-trinitrophenol |
RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer |
Immunogen | Notavailableorunknown |
ReportedApplications |
|
Endotoxin |
|
Purity |
|
Formulation |
|
Sterility | 0.2μMfiltered |
Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
Purification | ProteinG |
Storage | Undilutedat4°Cinthedark |
References
SDSSheet
品牌介绍
Bio X Cell采用最先进的发酵技术;包括搅拌罐发酵罐和波包系统;我们的生产能力从5升到500升不等。Bio X Cell提供从现有杂交瘤细胞系产生的抗体的生产和纯化服务。这些杂交瘤通常在客户的实验室中开发或在公共领域可用。该服务包括在细胞培养物中发酵杂交瘤,通过离心收获细胞培养上清液以及通过30 kDa超滤浓缩。通过蛋白A或G亲和色谱进行纯化。将纯化的抗体透析到PBS中并过滤除菌。我们所有定制产品的内毒素水平<2EU / mg。我们还提供冻结细胞系,现场细胞系存储和MAP测试的额外费用。
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