The30H12monoclonalantibodyreactswithmouseThy1.2alsoknownasCD90.2.Thy1.2isexpressedbythymocytesandmatureTlymphocytesaswellashematopoieticstemcells,neurons,epithelialcells,andfibroblasts.Thy1.2isexpressedonlybycertainmousestrainsincludingC57BL/6,BALB/c,CBA,C3H,C58/,SJL,DBA,andNZB/.Thy1.2isa25-35kDaGPI-anchoredmembraneglycoproteinandamemberoftheimmunoglobulinsuperfamily.ThefunctionofThy1.2hasnotbeenfullyelucidatedbutisthoughttoplayrolesincognition,axongrowth,Tlymphocytefunction,andapoptosis.The30H12monoclonalantibodyhasbeenreportedtoinduceCa2+fluxinthymocytes.ThisantibodyisparticularlyusefulfordepletionofTlymphocytes.
Isotype | RatIgG2b |
RecomendedIsotypeControl(s) | InVivoPlusratIgG2bisotypecontrol,anti-keyholelimpethemocyanin |
RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer |
Immunogen | Mousethymusorspleen |
ReportedApplications |
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Endotoxin |
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Purity |
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Aggregation |
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Formulation |
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Sterility | 0.2μMfiltered |
Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
Purification | ProteinG |
Storage | Undilutedat4°Cinthedark |
MurinePathogenTestResults |
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