The30H12monoclonalantibodyreactswithmouseThy1.2alsoknownasCD90.2.Thy1.2isexpressedbythymocytesandmatureTlymphocytesaswellashematopoieticstemcells,neurons,epithelialcells,andfibroblasts.Thy1.2isexpressedonlybycertainmousestrainsincludingC57BL/6,BALB/c,CBA,C3H,C58/,SJL,DBA,andNZB/.Thy1.2isa25-35kDaGPI-anchoredmembraneglycoproteinandamemberoftheimmunoglobulinsuperfamily.ThefunctionofThy1.2hasnotbeenfullyelucidatedbutisthoughttoplayrolesincognition,axongrowth,Tlymphocytefunction,andapoptosis.The30H12monoclonalantibodyhasbeenreportedtoinduceCa2+fluxinthymocytes.ThisantibodyisparticularlyusefulfordepletionofTlymphocytes.
| Isotype | RatIgG2b |
| RecomendedIsotypeControl(s) | InVivoPlusratIgG2bisotypecontrol,anti-keyholelimpethemocyanin |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer |
| Immunogen | Mousethymusorspleen |
| ReportedApplications |
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| Endotoxin |
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| Purity |
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| Aggregation |
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| Formulation |
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| Sterility | 0.2μMfiltered |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinG |
| Storage | Undilutedat4°Cinthedark |
| MurinePathogenTestResults |
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