TheRB6-8C5monoclonalantibodyreactsstronglywithmouseLy6GandweaklywithmouseLy6CpreviouslyreferredtoasGR-1.Ly6Gisa21-25kDamemberoftheLy-6superfamilyofGPI-anchoredcellsurfaceproteinswithrolesincellsignalingandcelladhesion.Ly6Gisexpresseddifferentiallyduringdevelopmentbycellsinthemyeloidlineageincludingmonocytesmacrophagesgranulocytesandneutrophils.MonocytestypicallyexpressLy6GtransientlyduringdevelopmentwhilematuregranulocytesandperipheralneutrophilsretainexpressionmakingLy6GagoodcellsurfaceMarkerforthesepopulations.TheRB6-8C5antibodyhasbeenshowntoinhibitthebindingofthe1A8antibody.The1A8monoclonalantibodyreactsspecificallywithmouseLy6GwithnoreportedcrossreactivitywithLy6C.
| Isotype | RatIgG2b, κ |
| RecomendedIsotypeControl(s) | InVivoPlusratIgG2bisotypecontrol,anti-keyholelimpethemocyanin |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer |
| Immunogen | Mousegranulocytes |
| ReportedApplications |
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| Endotoxin |
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| Purity |
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| Aggregation |
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| Formulation |
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| Sterility | 0.2μMfiltered |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinG |
| Storage | Undilutedat4°Cinthedark |
| MurinePathogenTestResults |
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