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BioXcell/InVivoMAb anti-mouse IL-23 (p19)/DISCOUNTED ACADEMIC OR NON PROFIT 25MG/BE0313-A025mg
AboutInVivoMAbanti-mouseFasL(CD178)
TheMFL3monoclonalantibodyreactswithmouseFasLigand(FasL)alsoknownasCD178,CD95Ligand,andTNFSF6.FasLisa40kDatypeIItransmembraneglycoproteinandamemberoftheTNFsuperfamily.FasLisexpressedonactivatedTcellsandinspleen,testis,andeye.UponbindingtoitsreceptorCD95(Fas)FasLinducesapoptoticcelldeathtomaintainperipheraltolerance.Sometumorsover-expressFasLandinducetheapoptosisofinfiltratinglymphocytes,allowingthetumortoescapetheeffectsofanimmuneresponse.CD178/CD95interactionsarealsothoughttoplayaroleintheproliferationofCD8+cellsandneutrophilextravasation,chemotaxisandsurvival.TheMFL3antibodyhasbeenreportedtoblockCD178/CD95inducedapoptosis.
InVivoMAbanti-mouseFasL(CD178)Specifications
| Isotype | ArmenianHamsterIgG |
| RecommendedIsotypeControl(s) | InVivoMAbpolyclonalArmenianhamsterIgG(BE0091) |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer(IP0070) |
| Immunogen | BHKcellsexpressingB6mouseFasL |
| ReportedApplications |
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| Formulation |
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| Endotoxin |
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| Purity |
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| Sterility | 0.2μMfiltered |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinA |
| MolecularWeight | 150kDa |
| RRID | AB_2819046 |
| Storage | Theantibodysolutionshouldbestoredatthestockconcentrationat4°C.Donotfreeze. |
