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BioXcell/InVivoMAb重组CTLA-4-Ig(hum/hum)/学术或非营利折扣:100MG/BE0099-A100mg
AboutInVivoMAbanti-human/monkeyCD40L(CD154)
The5C8monoclonalantibodyreactswithhumanandcynomolgusmonkeyCD154alsoknownasCD40ligand.CD154existsasa39kDaaccessorymoleculeandbelongstotheTNFsuperfamilyofcytokines.CD154isprimarilyexpressedonthesurfaceofactivatedCD4+Tlymphocytesbutcanalsobeexpressedbyplatelets,mastcells,macrophages,basophils,NKcells,Blymphocytes,CD8+Tlymphocytesaswellasnon-hematopoieticcellsincludingsmoothmusclecells,endothelialcells,andepithelialcells.CD154signalsthroughCD40andisthoughttoplayakeyroleinTandBlymphocyteco-stimulation.The5C8monoclonalantibodyhasbeenreportedtoblockCD40L-CD40interactions.
InVivoMAbanti-human/monkeyCD40L(CD154)Specifications
Isotype | MouseIgG2a |
RecommendedIsotypeControl(s) | InVivoMAbmouseIgG2aisotypecontrol,unknownspecificity(BE0085) |
RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer(IP0070) |
Immunogen | HumanD1.1Tcellline |
ReportedApplications |
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Endotoxin |
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Purity |
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Formulation | PBS,pH7.0 |
Sterility | 0.2μmfiltration |
Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
Purification | ProteinG |
Storage | Theantibodysolutionshouldbestoredatthestockconcentrationat4°C.Donotfreeze. |
RRID | AB_2687815 |
MolecularWeight | 150kDa |