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BioXcell/InVivoMAb anti-human LFA-1α (CD11a)/AMOUNT GREATER THAN 100 MG: (QUOTE ONLY)/BE0005-CUST
About InVivoMAb anti-human LFA-1α (CD11a)
The TS-1/22.1.1.13 monoclonal antibody reacts with human LFA-1α(lymphocyte function-associated antigen 1 alpha) also known as integrin alpha L chain and CD11a. LFA-1αand CD18 combine to form LFA-1 a 180 kDa glycoprotein and a member of the integrin family. LFA-1 is expressed on the surface of all leukocytes including lymphocytes monocytes macrophages and granulocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands ICAM-1 (CD54) ICAM-2 (CD102) and ICAM-3 (CD50) and also functions in lymphocyte costimulatory signaling.
InVivoMAb anti-human LFA-1α (CD11a) Specifications
| Isotype | Mouse IgG1 |
| Recommended Isotype Control(s) | InVivoMAb mouse IgG1 isotype control, unknown specificity(BE0083) |
| Recommended InVivoPure Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer(IP0070) |
| Immunogen | Human cytolytic T cells |
| Reported Applications | in vitro LFA-1 neutralization |
| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2 μM filtered |
| Production | Purified from tissue culture supernatant in an animal free facility |
| Purification | Protein G |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
| RRID | AB_1107580 |
| Molecular Weight | 150 kDa |
