4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:主营:抗体类,InVivo Mab抗体,InVivo Plus抗体,InVivo纯稀释缓冲液,ReadyTag抗体,融合蛋白
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > Functional_antibody > BioXcell/InVivoMAb抗小鼠IL-23(p19)/常规25MG/BE0313-R025mg
商品详细BioXcell/InVivoMAb抗小鼠IL-23(p19)/常规25MG/BE0313-R025mg
BioXcell/InVivoMAb抗小鼠IL-23(p19)/常规25MG/BE0313-R025mg
BioXcell/InVivoMAb抗小鼠IL-23(p19)/常规25MG/BE0313-R025mg
商品编号: BE0313-R025mg
品牌: BioXcell inc
市场价: ¥33000.00
美元价: 19800.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

AboutInVivoMAbanti-mouseIL-23(p19)

TheG23-8monoclonalantibodyreactswiththep19subunitofmouseIL-23.IL-23isaheterodimericcytokinecomposedoftwodisulfide-linkedsubunits,ap19subunitthatisuniquetoIL-23,andap40subunitthatissharedwithIL-12.IL-23issecretedbyactivateddendriticcellsandmacrophages.IL-23hasbeenshowntoenhanceIFNγproductionbymemoryTcells.Additionally,mouseIL-23inducestheproliferationofmemoryTcells(butnotnaiveTcells),whereasIL-12hasnoeffectonmemorycells.MouseIL-23(butnotIL-12)canalsoactivatemousememoryTcellstoproducethepotentproinflammatorycytokineIL-17.IL-23hasbeenshowntobeupregulatedincertainautoimmunediseasesandpromoteimmunityinresponsetosomeviralandmycobacterialinfections.TheG23-8antibodycanspecificallyneutralizeIL-23bioactivitywithnoeffectonIL-12p70bioactivity.

InVivoMAbanti-mouseIL-23(p19)Specifications

Isotype

RatIgG1,κ

RecommendedIsotypeControl(s)InVivoMAbratIgG1isotypecontrol,anti-horserADIshperoxidase(BE0088)
RecommendedInVivoPureDilutionBufferInVivoPurepH7.0DilutionBuffer(IP0070)
Immunogen

Insectcell-expressed,recombinantmouseIL-23heterodimer

ReportedApplications
  • invivoIL-23p19neutralization
  • Westernblot
Formulation
  • PBS,pH7.0
  • ContainsnostABIlizersorpreservatives
Endotoxin
  • <2EU/mg(<0.002EU/μg)
  • DeterminedbyLALgelclottingassay
Purity
  • >95%
  • DeterminedbySDS-PAGE
Sterility

0.2μMfiltered

Production

Purifiedfromtissueculturesupernatantinananimalfreefacility

Purification

ProteinG

RRID

AB_2754551

MolecularWeight

150kDa

Storage

Theantibodysolutionshouldbestoredatthestockconcentrationat4°C.Donotfreeze.

品牌介绍
Bio X Cell采用最先进的发酵技术;包括搅拌罐发酵罐和波包系统;我们的生产能力从5升到500升不等。Bio X Cell提供从现有杂交瘤细胞系产生的抗体的生产和纯化服务。这些杂交瘤通常在客户的实验室中开发或在公共领域可用。该服务包括在细胞培养物中发酵杂交瘤,通过离心收获细胞培养上清液以及通过30 kDa超滤浓缩。通过蛋白A或G亲和色谱进行纯化。将纯化的抗体透析到PBS中并过滤除菌。我们所有定制产品的内毒素水平<2EU / mg。我们还提供冻结细胞系,现场细胞系存储和MAP测试的额外费用。