About InVivoPlus anti-mouse VEGFR-2
The DC101 monoclonal antibody reacts with mouse VEGFR-2 (vascular endothelial growth factor receptor 2) also known as CD309, KDR, and Flk-1. VEGFR-2 is a member of the tyrosine protein kinase family. Upon binding to its ligand VEGF, VEGFR-2 pays key roles in vascular development and permeability. VEGFR-2 is expressed on endothelial cells at high levels in adult heart, lung, kidney, brain, and skeletal muscle as well as other tissues at lower levels. The DC101 antibody has been shown to inhibit VEGFR-2 signaling in vivo.
InVivoPlus anti-mouse VEGFR-2 Specifications
| Isotype | Rat IgG1, κ |
| Recommended Isotype Control(s) | InVivoPlus rat IgG1 isotype control, anti-horseradish peroxidase(BP0088) |
| Recommended InVivoPure Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer(IP0070) |
| Immunogen |
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| Reported Applications |
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| Endotoxin |
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| Binding Validation | Determined by immunoblot |
| Purity |
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| Aggregation |
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| Formulation |
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| Sterility | 0.2 μM filtered |
| Production | Purified from tissue culture supernatant in an animal free facility |
| Purification | Protein G |
| Molecular Weight | 150 kDa |
| Murine Pathogen Test Results |
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| RRID | AB_1107766 |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
