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BioXcell/InVivoMAb anti-mouse CD45.2/DISCOUNTED ACADEMIC OR NON PROFIT 5MG/BE0300-A005mg
About InVivoMAb anti-mouse CD45.2
The 104.2 monoclonal antibody reacts with mouse CD45.2 a 180-240 kDa member of the protein tyrosine phosphatase family. CD45.2 is an alloantigen of CD45 and is only expressed by certain mouse strains including C57BL/6, CBA, 129, A, AKR, C58, DBA/1, DBA/2, BALB/c, and C3H/He. The 104.2 monoclonal antibody does not react with leukocytes of CD45.1-expressing mouse strains including DA, SJL/J, RIII, and STS/A. CD45.2 is expressed on all hematopoietic cells except mature erythrocytes and platelets and is thought to be involved in TCR and BCR signal transduction. The 104.2 antibody has been shown to block B cell responses in vitro and reduce serum autoantibody concentration in vivo in SLE-prone mice.
InVivoMAb anti-mouse CD45.2 Specifications
| Isotype | Mouse IgG2a, κ |
| Recommended Isotype Control(s) | InVivoMAb mouse IgG2a isotype control, unknown specificity(BE0085) |
| Recommended InVivoPure Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer(IP0070) |
| Immunogen | B10.S mouse thymocytes and splenocytes |
| Reported Applications |
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| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2 μm filtration |
| Production | Purified from tissue culture supernatant in an animal free facility |
| Purification | Protein G |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
| RRID | AB_2715458 |
| Molecular Weight | 150 kDa |
