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BioXcell/InVivoPlus anti-mouse IFNAR-1/DISCOUNTED ACADEMIC OR NON PROFIT 5MG/BP0241-A005mg
About InVivoPlus anti-mouse IFNAR-1
The MAR1-5A3 monoclonal antibody reacts with mouse IFNAR-1 (IFN alpha/beta receptor subunit 1). IFNAR-1 is coexpressed with IFNAR-2 on nearly all cell types and together these two subunits make up the heterodimeric Type I IFN Receptor complex. Type I IFNs (IFN-α/β) bind to the Type I IFN Receptor complex to induce cellular responses including induction of anti-viral, anti-microbial, anti-tumor, and autoimmune responses as well as to regulate the activation, proliferation, and differentiation of many cell types. The MAR1-5A3 antibody has been shown to inhibit Type I IFN receptor signaling in vitro and in vivo.
InVivoPlus anti-mouse IFNAR-1 Specifications
Isotype | Mouse IgG1, κ |
Recommended Isotype Control(s) | InVivoPlus mouse IgG1 isotype control, unknown specificity(BP0083) |
Recommended InVivoPure Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer(IP0070) |
Immunogen | Extracellular domain of mouse IFNAR-1 |
Reported Applications |
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Endotoxin |
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Binding Validation | Determined by immunoblot |
Purity |
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Aggregation |
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Binding Validation | Determined by immunoblot |
Formulation |
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Sterility | 0.2 μM filtered |
Production | Purified from tissue culture supernatant in an animal free facility |
Molecular Weight | 150 kDa |
Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
Murine Pathogen Test Results |
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RRID | AB_2687723 |
Purification | Protein G |