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BioXcell/InVivoMAb anti-mouse TIM-1 (CD365)/REGULAR 5MG/BE0314-R005mg
About InVivoMAb anti-mouse TIM-1 (CD365)
The 3D10 monoclonal antibody reacts with mouse T cell immunoglobulin and mucin domain 1 (TIM-1) also known as CD365. TIM-1 is a type I cell-surface glycoprotein and member of the Ig superfamily. TIM-1 is preferentially expressed on TH2 cells and has been identified as a stimulatory molecule for T cell activation. The TIM gene family, plays critical roles in regulating the immune response to viral infection. TIM-1 is also involved in allergic responses, asthma, and transplant tolerance. The 3D10 antibody has been shown to block TIM-1 in vivo and enhance atherosclerosis in mice studies.
InVivoMAb anti-mouse TIM-1 (CD365) Specifications
| Isotype | Rat IgG1, κ |
| Recommended Isotype Control(s) | InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase(BE0088) |
| Recommended InVivoPure Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer(IP0070) |
| Immunogen | Mouse TIM-1 (signal and IgV domains)/mouse IgG2a Fc fusion protein |
| Reported Applications |
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| Formulation |
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| Endotoxin |
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| Purity |
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| Sterility | 0.2 μM filtered |
| Production | Purified from tissue culture supernatant in an animal free facility |
| Purification | Protein G |
| RRID | AB_2754552 |
| Molecular Weight | 150 kDa |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
