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BioXcell/InVivoMAb anti-mouse CD70/AMOUNT GREATER THAN 100 MG: (QUOTE ONLY)/BE0022-CUST
About InVivoMAb anti-mouse CD70
The FR70 monoclonal antibody reacts with mouse CD70, a 30-33 kDa type II transmembrane glycoprotein and a member of the TNF superfamily. CD70 is expressed by activated mouse T and B lymphocytes and dendritic cells. CD70 is a ligand for CD27 and their interaction promotes T and B cell cross-stimulation and co-stimulation of B cell proliferation and immunoglobulin production. Cells expressing CD70 have been shown to co-stimulate T cell proliferation and induce cytokine production. The FR70 antibody is reported to block CD70 binding to CD27.
InVivoMAb anti-mouse CD70 Specifications
| Isotype | Rat IgG2b, κ |
| Recommended Isotype Control(s) | InVivoMAb rat IgG2b isotype control, anti-keyhole limpet hemocyanin(BE0090) |
| Recommended InVivoPure Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer(IP0070) |
| Immunogen | BALB/c mouse B lymphoma A20.2J |
| Reported Applications |
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| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2 μM filtered |
| Production | Purified from tissue culture supernatant in an animal free facility |
| Purification | Protein G |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
| RRID | AB_1107667 |
| Molecular Weight | 150 kDa |
