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BioXcell/InVivoMAb抗小鼠CTLA-4（CD152）/折扣学术或非营利性100MG/BE0131-A100mg
About InVivoMAb anti-human/monkey CD40L (CD154)
The 5C8 monoclonal antibody reacts with human and cynomolgus monkey CD154 also known as CD40 ligand. CD154 exists as a 39 kDa accessory molecule and belongs to the TNF superfamily of cytokines. CD154 is primarily expressed on the surface of activated CD4+ T lymphocytes but can also be expressed by platelets, mast cells, macrophages, basophils, NK cells, B lymphocytes, CD8+ T lymphocytes as well as non-hematopoietic cells including smooth muscle cells, endothelial cells, and epithelial cells. CD154 signals through CD40 and is thought to play a key role in T and B lymphocyte co-stimulation. The 5C8 monoclonal antibody has been reported to block CD40L-CD40 interactions.
InVivoMAb anti-human/monkey CD40L (CD154) Specifications
| Isotype | Mouse IgG2a |
| Recommended Isotype Control(s) | InVivoMAb mouse IgG2a isotype control, unknown specificity(BE0085) |
| Recommended InVivoPure Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer(IP0070) |
| Immunogen | Human D1.1 T cell line |
| Reported Applications |
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| Endotoxin |
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| Purity |
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| Formulation | PBS, pH 7.0 |
| Sterility | 0.2 μm filtration |
| Production | Purified from tissue culture supernatant in an animal free facility |
| Purification | Protein G |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
| RRID | AB_2687815 |
| Molecular Weight | 150 kDa |
