About InVivoMAb anti-mouse Notch4
The HMN4-14 monoclonal antibody reacts with mouse neurogenic locus notch homolog 4 (Notch4) a member of the Notch family of type 1 transmembrane proteins. The Notch signaling pathway is a highly conserved intercellular signaling pathway. Five Notch ligands have been identified including DLL4 and Jagged2. Upon ligand binding the Notch receptor undergoes proteolysis and translocates to the nucleus ultimately activating transcription. The Notch pathway has been shown to play a role in myeloid cell proliferation, hematopoiesis, and embryonic endothelial development.
InVivoMAb anti-mouse Notch4 Specifications
| Isotype | Armenian Hamster IgG, κ |
| Recommended Isotype Control(s) | InVivoMAbpolyclonal Armenian hamster IgG(BE0091) |
| Recommended InVivoPure Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer(IP0070) |
| Immunogen | Notch4-Fc recombinant protein |
| Reported Applications |
|
| Endotoxin |
|
| Purity |
|
| Formulation |
|
| Sterility | 0.2 μM filtered |
| Production | Purified from tissue culture supernatant in an animal free facility |
| Purification | Protein G |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
| RRID | AB_10948996 |
| Molecular Weight | 150 kDa |
