>
产品中心 >
Functional_antibody >
BioXcell/InVivoMAb anti-mouse CD200 (OX2)/REGULAR 1MG/BE0299-R001mg
AboutInVivoMAbanti-mouseCD200(OX2)
TheOX-90monoclonalantibodyreactswithmouseCD200alsoknownasOX2.CD200isatype1membraneglycoproteinbelongingtotheimmunoglobulinsuperfamily.CD200expressionislimitedtothymocytes,neurons,Bcells,splenicfolliculardendriticcellsandendothelium,andsubsetsofTcellsanddendriticcells.CD200hasbeenshowntoco-stimulateTcellproliferation.ItisthoughtthatengagementofCD200withitsreceptor,CD200R,resultsininhibitionand/ordownregulationofmyeloidcellactivity. Blockingthisinteractiondecreasestheinhibitorythresholdsofmyeloidcellsresultinginincreasedimmuneactivity.TheOX-90antibodyhasbeenreportedtoblockthebindingofCD200toCD200Rinvivo.
InVivoMAbanti-mouseCD200(OX2)Specifications
| Isotype | RatIgG2a,κ |
| RecommendedIsotypeControl(s) | InVivoMAbratIgG2aisotypecontrol,anti-trinitrophenol(BE0089) |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer(IP0070) |
| Immunogen | FusionproteinconsistingofmouseCD200(extracellularregion)andratCD4(domains3and4) |
| ReportedApplications |
|
| Endotoxin |
|
| Purity |
|
| Formulation |
|
| Sterility | 0.2μmfiltration |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinG |
| Storage | Theantibodysolutionshouldbestoredatthestockconcentrationat4°C.Donotfreeze. |
| RRID | AB_2687821 |
| MolecularWeight | 150kDa |
