About InVivoMAb anti-rat Kappa Immunoglobulin Light Chain
The MAR 18.5 monoclonal antibody reacts with the kappa chain of the rat immunoglobulin light chain. The κ chain is one of two types of polypeptide subunits which make up the immunoglobulin light chain. A typical antibody is composed of two immunoglobulin heavy chains and two immunoglobulin light chains. The κ chain is coded for by V (variable), J (joining) and C (constant) genes. These genes undergo V(D)J recombination to generate a diverse repertoire of immunoglobulins. This antibody is used in combination with rat anti-mouse CD19 and CD22 (clones 1D3 and Cγ34.1) to deplete B cells in vivo.
InVivoMAb anti-rat Kappa Immunoglobulin Light Chain Specifications
Isotype | Mouse IgG2a, κ |
Recommended Isotype Control(s) | InVivoMAb mouse IgG2a isotype control, unknown specificity(BE0085) |
Recommended InVivoPure Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer(IP0070) |
Immunogen | Soluble rat immunoglobulin |
Reported Applications | in vivo B cell depletion in combination with anti-CD19 (clone 1D3) and anti-CD22 (clone Cy34.1) |
Endotoxin |
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Purity |
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Formulation |
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Sterility | 0.2 μM filtered |
Production | Purified from tissue culture supernatant in an animal free facility |
Purification | Protein G |
Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
RRID | AB_10951292 |
Molecular Weight | 150 kDa |