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BioXcell/InVivoMAb anti-mouse CD3ε/REGULAR: 5MG/BE0261-R005mg
AboutInVivoMAbanti-ratβ-2-Microglobulin
The4C9monoclonalantibodyreactswithratbeta2microglobulin(β2M)a12kDacomponentofMHCclassImolecules.β-2-microglobulin,anon-membrane-anchoredglycoprotein,noncovalentlyassociateswiththepolymorphicheavychainofMHCclassImoleculestoformtheHLAclassIantigencomplex.β-2-microglobulinisexpressedonallleukocytes,platelets,endothelialcellsandepithelialcellsandplaysanessentialroleinmediatingproperfoldingandexpressionofMHCclassImolecules.Theimportanceofβ-2-microglobulinisillustratedbyβ-2-microglobulinknockoutmicewhichshowanormaldistributionofTlymphocytes,buthavenomatureCD4orCD8TcellsandarethereforedefectiveinCD4andCD8Tcell-mediatedcytotoxicity.The4C9antibodyrecognizesratβ-2-microglobulinaloneorcomplexedwithFcRnheavychains.
InVivoMAbanti-ratβ-2-MicroglobulinSpecifications
| Isotype | MouseIgG1 |
| RecommendedIsotypeControl(s) | InVivoMAbmouseIgG1isotypecontrol,unknownspecificity(BE0083) |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer(IP0070) |
| Immunogen | SolubleneonatalFcreceptor(FcRn) |
| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2μMfiltered |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinG |
| Storage | Theantibodysolutionshouldbestoredatthestockconcentrationat4°C.Donotfreeze. |
| RRID | AB_10951294 |
| MolecularWeight | 150kDa |
