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BioXcell/InVivoMAb human IgG1 isotype control/REGULAR 50MG/BE0297-R050mg
AboutInVivoMAbanti-human/monkeyCD40L(CD154)
The5C8monoclonalantibodyreactswithhumanandcynomolgusmonkeyCD154alsoknownasCD40ligand.CD154existsasa39kDaaccessorymoleculeandbelongstotheTNFsuperfamilyofcytokines.CD154isprimarilyexpressedonthesurfaceofactivatedCD4+Tlymphocytesbutcanalsobeexpressedbyplatelets,mastcells,macrophages,basophils,NKcells,Blymphocytes,CD8+Tlymphocytesaswellasnon-hematopoieticcellsincludingsmoothmusclecells,endothelialcells,andepithelialcells.CD154signalsthroughCD40andisthoughttoplayakeyroleinTandBlymphocyteco-stimulation.The5C8monoclonalantibodyhasbeenreportedtoblockCD40L-CD40interactions.
InVivoMAbanti-human/monkeyCD40L(CD154)Specifications
| Isotype | MouseIgG2a |
| RecommendedIsotypeControl(s) | InVivoMAbmouseIgG2aisotypecontrol,unknownspecificity(BE0085) |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer(IP0070) |
| Immunogen | HumanD1.1Tcellline |
| ReportedApplications |
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| Endotoxin |
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| Purity |
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| Formulation | PBS,pH7.0 |
| Sterility | 0.2μmfiltration |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinG |
| Storage | Theantibodysolutionshouldbestoredatthestockconcentrationat4°C.Donotfreeze. |
| RRID | AB_2687815 |
| MolecularWeight | 150kDa |
