4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:主营:抗体类,InVivo Mab抗体,InVivo Plus抗体,InVivo纯稀释缓冲液,ReadyTag抗体,融合蛋白
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > Antibody_set > BioXcell/ReadyTag anti-GFP/AMOUNT GREATER THAN 100 MG: (QUOTE ONLY)/RT0265-CUST
商品详细BioXcell/ReadyTag anti-GFP/AMOUNT GREATER THAN 100 MG: (QUOTE ONLY)/RT0265-CUST
BioXcell/ReadyTag anti-GFP/AMOUNT GREATER THAN 100 MG: (QUOTE ONLY)/RT0265-CUST
BioXcell/ReadyTag anti-GFP/AMOUNT GREATER THAN 100 MG: (QUOTE ONLY)/RT0265-CUST
商品编号: RT0265-CUST
品牌: BioXcell inc
市场价: ¥49000.00
美元价: 29400.00
产地: 美国(厂家直采)
公司:
产品分类: 抗体套装
公司分类: Antibody_set
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

About InVivoMAb anti-mouse CD19

The 1D3 monoclonal antibody reacts with mouse CD19, a B cell-specific 95 kDa transmembrane glycoprotein of the immunoglobulin superfamily. CD19 contains two extracellular immunoglobulin-like domains and an extensive cytoplasmic tail. It functions as a positive regulator of B-cell receptor signaling in conjunction with CD21 and CD81. CD19 is highly expressed in most lymphomas and leukemias including some early B-cell malignancies that do not express CD20. For these reasons CD19 is quickly becoming an attractive alternative target for the immunotherapy of lymphoproliferative disorders. The 1D3 antibody has been reported to deplete B cells however, B cell depletion often requires treatment with a combination of 1D3, anti-mouse B220 (clone RA3.3A1/6.1), anti-mouse CD22 (clone Cy34.1), and anti-rat κ light chain (clone MAR 18.5) antibodies. Please see the provided references for protocol details.

InVivoMAb anti-mouse CD19 Specifications

Isotype

Rat IgG2a, κ

Recommended Isotype Control(s)InVivoMAb rat IgG2a isotype control, anti-trinitrophenol(BE0089)
Recommended InVivoPure Dilution BufferInVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen

K562 cells expressing the extracellular domain of mouse CD19

Reported Applications
  • in vivo B cell depletion
  • in vivo CD19 neutralization
  • in vitro B cell negative selection
  • Flow cytometry
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.

RRID

AB_10949187

Molecular Weight

150 kDa

品牌介绍
Bio X Cell采用最先进的发酵技术;包括搅拌罐发酵罐和波包系统;我们的生产能力从5升到500升不等。Bio X Cell提供从现有杂交瘤细胞系产生的抗体的生产和纯化服务。这些杂交瘤通常在客户的实验室中开发或在公共领域可用。该服务包括在细胞培养物中发酵杂交瘤,通过离心收获细胞培养上清液以及通过30 kDa超滤浓缩。通过蛋白A或G亲和色谱进行纯化。将纯化的抗体透析到PBS中并过滤除菌。我们所有定制产品的内毒素水平<2EU / mg。我们还提供冻结细胞系,现场细胞系存储和MAP测试的额外费用。