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当前位置: 首页 > 产品中心 > monoclonal_antibody > BioXcell/InVivoPlus anti-mouse PD-1 (CD279)/REGULAR: 5MG/BP0033-2-R005mg
商品详细BioXcell/InVivoPlus anti-mouse PD-1 (CD279)/REGULAR: 5MG/BP0033-2-R005mg
BioXcell/InVivoPlus anti-mouse PD-1 (CD279)/REGULAR: 5MG/BP0033-2-R005mg
BioXcell/InVivoPlus anti-mouse PD-1 (CD279)/REGULAR: 5MG/BP0033-2-R005mg
商品编号: BP0033-2-R005mg
品牌: BioXcell inc
市场价: ¥65000.00
美元价: 39000.00
产地: 美国(厂家直采)
公司:
产品分类: 单克隆抗体
公司分类: monoclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

About InVivoMAb anti-mouse PD-L2 (B7-DC)

The TY25 monoclonal antibody reacts with mouse PD-L2 (programmed death ligand 2) also known as B7-DC or CD273. PD-L2 is a 25 kDa type I transmembrane protein that belongs to the B7 family of the Ig superfamily. PD-L2 is expressed on monocytes, macrophages and subsets of dendritic cells. PD-L2 binds to its receptor, PD-1, found on CD4 and CD8 thymocytes as well as activated T and B lymphocytes and myeloid cells. Engagement of PD-L2 with PD-1 leads to inhibition of TCR-mediated T cell proliferation and cytokine production. The TY25 antibody has been reported to block PD-1 mediated interactions in vivo.

InVivoMAb anti-mouse PD-L2 (B7-DC) Specifications

Isotype

Rat IgG2a, κ

Recommended Isotype Control(s)InVivoMAb rat IgG2a isotype control, anti-trinitrophenol(BE0089)
Recommended InVivoPure Dilution BufferInVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen

Mouse PD-L2 transfected cell line

Reported Applications
  • in vivo PD-L2 blockade
  • in vitro PD-L2 blockade
  • Immunohistochemistry (frozen)
  • Flow cytometry
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assy
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.

RRID

AB_10950106

Molecular Weight

150 kDa

品牌介绍
Bio X Cell采用最先进的发酵技术;包括搅拌罐发酵罐和波包系统;我们的生产能力从5升到500升不等。Bio X Cell提供从现有杂交瘤细胞系产生的抗体的生产和纯化服务。这些杂交瘤通常在客户的实验室中开发或在公共领域可用。该服务包括在细胞培养物中发酵杂交瘤,通过离心收获细胞培养上清液以及通过30 kDa超滤浓缩。通过蛋白A或G亲和色谱进行纯化。将纯化的抗体透析到PBS中并过滤除菌。我们所有定制产品的内毒素水平<2EU / mg。我们还提供冻结细胞系,现场细胞系存储和MAP测试的额外费用。