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BioXcell/InVivoPlus rat IgG1 isotype control, anti-trinitrophenol/REGULAR: 100MG/BP0290-R100mg
About InVivoMAb anti-human CD11a (LFA-1α)
The R7-1 monoclonal antibody reacts with human LFA-1α (lymphocyte function-associated antigen 1 alpha) also known as integrin alpha L chain and CD11a. Specifically, this antibody recognizes an epitope within the I-domain of LFA-1α. LFA-1α and CD18 combine to form LFA-1, a 180 kDa glycoprotein and a member of the integrin family. LFA-1 is expressed on the surface of all leukocytes including lymphocytes, monocytes, macrophages, and granulocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50), and also functions in lymphocyte costimulatory signaling. The R7-1 antibody is a neutralizing antibody.
InVivoMAb anti-human CD11a (LFA-1α) Specifications
| Isotype | Mouse IgG1 |
| Recommended Isotype Control(s) | InVivoMAb mouse IgG1 isotype control, unknown specificity(BE0083) |
| Recommended InVivoPure Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer(IP0070) |
| Immunogen | Not available or unknown |
| Reported Applications |
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| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2 μM filtered |
| Production | Purified from tissue culture supernatant in an animal free facility |
| Purification | Protein G |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
| RRID | AB_10948991 |
| Molecular Weight | 150 kDa |
