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BioXcell/InVivoPlus大鼠IgG1同型对照，抗辣根过氧化物酶/常规：50MG/BP0088-R050mg
About InVivoMAb anti-mouse TNFR2 (CD120b)
The TR75-54.7 monoclonal antibody reacts with mouse Tumor Necrosis Factor Receptor Type II (TNFR2) also known as CD120b, TNFR type II, and p75. TNFR2 is expressed on many cell types at low levels; upon activation the expression is upregulated. Upon binding either of its two ligands, TNFα or LTα (lymphotoxin alpha) TNFR2 signal transduction leads to a wide spectrum of biological processes including immunoregulation, cell proliferation, differentiation, apoptosis, NF-kB activation, increased expression of proinflammatory genes, antitumor activity, inflammation, anorexia, cachexia, septic shock, hematopoiesis, and viral replication. The TR75-54.7 antibody has been reported to block ligand-induced receptor signaling.
InVivoMAb anti-mouse TNFR2 (CD120b) Specifications
| Isotype | Armenian Hamster IgG |
| Recommended Isotype Control(s) | InVivoMAbpolyclonal Armenian hamster IgG(BE0091) |
| Recommended InVivoPure Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer(IP0070) |
| Immunogen | Recombinant mouse TNFR2 |
| Reported Applications |
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| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2 μM filtered |
| Production | Purified from tissue culture supernatant in an animal free facility |
| Purification | Protein G |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
| RRID | AB_2687728 |
| Molecular Weight | 150 kDa |
